ea0022p159 | Cardiovascular endocrinology and lipid metabolism | ECE2010
Drapalova Jana
, Kotulak Tomas
, Kopecky Petr
, Mraz Milos
, Riha Hynek
, Blaha Jan
, Kramar Petr
, Netuka Ivan
, Maly Jan
, Kremen Jaromir
, Kotrlikova Eva
, Svacina Stepan
, Haluzik Martin
Introduction: Fibroblast growth factor-21 (FGF-21) is a novel regulator of glucose and lipid metabolism and insulin sensitivity. Possible role of FGF-21 in the development of insulin resistance in critically ill patients has not been studied yet.Objective: To study the changes in FGF21 production and adipose tissue and skeletal muscle FGF-21 mRNA gene expression in cardiac surgery patients.Methods: Sixteen patients (16 men, aged 66...